TY - JOUR TI - Computational role of blood-based casson fluid-flow through a stenotic artery: An application to cardiovascular issues AU - Suneetha Sangapatnam AU - Ramasekhar Gunisetty JN - Thermal Science PY - 2025 VL - 29 IS - 4 SP - 3267 EP - 3277 PT - Article AB - The living muscular system’s blood circulation structure includes veins with nanoparticles. Flowing blood is non-Newtonian throughout vessel section. The stenosed artery interior is taken into account. Iron (III) oxide (F2O3) and silver nanoparticles have several biological uses because they oxidize quicker when compared to other nanoparticles throughout the blood and purify blood within the stenosed artery. Atherosclerosis channels decrease cardiovascular function. It may restrict blood flow to your heart and brain. Based on the motivation, the present framework’s primary goal is to investigate the significance of Fe2O3 and silver nanoparticles in red blood cells in the existence of MHD within a stenotic artery. The flow problem is highly non-linear coupled PDE, which are transformed into ODE with the help of similarity variables. These are solved numerically using the bvp5c method in MATLAB software. In order to facilitate the presentation of the theoretical outcomes of this drug delivery mechanism. The use of F2O3 and silver nanoparticles used in medical delivery agent. For instance, as expected, a decrease in blood circulation occurred when the parameter for magnetic fields was increased in an effort to enhance the magnetic characteristics of the living organisms composing the bloodstream. Increasing the flow parameter values enhanced the temperature profile. The findings of this study have important implications for the fields of healthcare engineering. Heat treatment, targeted drug delivery, and ultrasound imaging among all areas that might benefit from its use in the medical field.