TY - JOUR TI - Innovative mathematical modelling approaches to diagnose chronic neurological disorders with deep learning AU - Karim Faten K AU - Ghorashi Sara AU - Ishak Anis Ben AU - Elhag Azhari A AU - Mohamed Nahla JN - Thermal Science PY - 2024 VL - 28 IS - 6 SP - 5217 EP - 5229 PT - Article AB - Multiple sclerosis impacts the central nervous system, causing symptoms like fatigue, pain, and motor impairments. Diagnosing multiple sclerosis often requires complex tests, and MRI analysis is critical for accuracy. Machine learning has emerged as a key tool in neurological disease diagnosis. This paper introduces the multiple sclerosis diagnosis network (MSDNet), a stacked ensemble of deep learning classifiers for multiple sclerosis detection. The MSDNet uses min-max normalization, the artificial hummingbird algorithm for feature selection, and a combination of LSTM, DNN, and CNN models. Hyperparameters are optimized using the enhanced walrus optimization algorithm. Experimental results show MSDNet's superior performance compared to recent methods.