TY - JOUR
TI - The silent assassin: Empirical formulas, molar masses, biosynthesis reactions, enthalpies, entropies and Gibbs energies of biosynthesis and Gibbs energies of binding of Coxsackieviruses A and B
AU - Popović Marko E
AU - Šekularac Gavrilo
AU - Tadić Vojin
AU - Pantović-Pavlović Marijana
JN - Thermal Science
PY - 2024
VL - 28
IS - 6
SP - 4737
EP - 4757
PT - Article
AB - Coxsackievirus B represents a nightmare for a large number of medical staff. Due to exposure to Coxsackievirus in closed spaces (ambulances and waiting rooms), infections by Coxsackievirus B are a common occurrence. This paper for the first time reports chemical and thermodynamic properties of Coxsackieviruses A and B, and offers a mechanistic model of Coxsackievirus-host interaction. The driving force of the interaction at the membrane (antigen-receptor binding) is Gibbs energy of binding. The driving force of virus-host interaction in the cytoplasm is Gibbs energy of biosynthesis. This paper analyzes the mechanism of hijacking of cell metabolic machinery of susceptible cells.